Many traps are possible with solid state !
That is why a complete knowledge of cristalline forms is very important for pharma development.
❕ The more we know about polymorphic forms, the better.
If having fully characterized the targeted crystal form is necessary, knowledge on the other undesired solid forms is critical and highly recommended.
Why ?
Because knowing in which conditions the undesired crystal forms could appear gives us the opportunity to control them and thus to be sure that they will not arrive, not disturb the pharma development.
Which traps are we talking about ?
Hydrate/solvate, a more stable polymorphic form, monotropy/enantiotropy, non congruente solubility, …
👉 Solid state screenings allow to generate such data.
👨🔬 Holodiag is your expert CRO for polymorphs, cocrystals and salts screenings.
#screenings #crystals #pharma
