Cocrystals for pharma development
Cocrystal is an interesting crystalline structure for pharma development (bioavailabity, solubility).
Dedicated investigations must be performed for identification : the so-called screening.
Then further studies are necessary for an accurate description of the specific features (non-congruent solubility).
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XRPD is the main technique for characterization of pharmaceutical solids
It is used for: ◾ formulation control, ◾ crystallinity or…
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Undesired particles in liquid formulation
Undesired particles in liquid formulation Particles in liquid formulation…
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Many traps are possible with solid state !
That is why a complete knowledge of cristalline forms is…
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Undesired polymorphic forms can be contemplated as crystalline impurities
Access to reference samples of such crystalline impurities is a…
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