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☑ Holodiag is now FDA registered for its analytical services (XRPD, DVS, DSC, Laser PSD, TGA, ...).Congratulations to the team for this achievement!#FDA #pharma #analyses #QC Check it on FDA website !

The density of a powder is important data in pharmaceutical development. 💡 It provides information on its flowability and its capacity to make a tablet. Holodiag offers bulk and tapped density measurement services compliant with the Pharmacopoeia (Hausner index), including on toxic products. #analyticalservices #density #powder #pharma More about analytical services

📈 Intrinsic dissolution allows to measure the speed of dissolution of a drug substance (pure API).As integral part of API solid form characterization, it is key data for relevant form selection, bioavailability calculations and solid state dissolution comparisons between various crystal forms.As an expert in solubility measurements, Holodiag offers intrinsic dissolution rate…

How to solve polymorphic form, identification, purity profil, LOD in drug substance and drug product ?Our services are applicable on pure API, tablets, suspensions, ointments, ...Ask Holodiag for XRPD method development and validation. Analysis features

A second Dynamic Vapor Sorption (DVS) device has joigned the lab ! Our systems allow to monitor sample mass variation vs. Relative Humidity (RH). Our lab facilities

A second X-Ray Powder Diffratometer from Malvern Panalytical has joined Holodiag's lab ! Meet the twins right bellow ! Our lab equipments

Holodiag's analytical methods are apllicable to toxic samples down to 50 ng/m3. Thanks to laminar flow hood systems, HPAPIs, cytotoxic compounds and CMR substances can be handled with high security by our scientific team. Example of equipments under protection:• our Malvern Mastersizer 3000 for particle size distribution (Laser PSD)• our Dynamic Vapor…

Indeed, these analyses allow to get information about: • melting • (re)crystallization • stable/metastable phases • monotropy/nantiotropy • amorphous/Tg • hydrates/solvates • decomposition/degradation • temperature • enthalpy • stability • compatibility and more ! Holodiag owns a Mettler DSC 3+ and TGA-DSC 3+. Get to know more about these techniques

InfraRed is a well-known technique for molecular structure identification. It is also used to identify polymorphism in solid samples. Holodiag performs these analyses on high potent product down to 50 ng/m3. About ThermoFisher Nicolet iS5 spectrometer

Particle size and shape are crucial parameters in the pharmaceutical industry because it influences many material properties. Consequences are numerous especially for filtration and drying steps. Holodiag provides advanced analytical services for PSD with a Mastersizer 3000 with both dry and liquid mode. Such a system is fully set and qualified under…

Various formulations can be analyzed by XRPD to identify the crystal form of an API. Among classical ones, there are: • spray• suppository• capsule• transdermal patche• suspension• ointment• tablet• powder But also unexpected ones ! As: • flea collar• chew stick• IUD for cow• medicated nail polish Get to know more about XRPD analysis