TGA and DSC are key thermal analyses for solid state characterization
Indeed, these analyses allow to get information about: • melting • (re)crystallization • stable/metastable phases • monotropy/nantiotropy • amorphous/Tg • hydrates/solvates • decomposition/degradation • temperature • enthalpy • stability • compatibility and more ! Holodiag owns a Mettler DSC 3+ and TGA-DSC 3+.
Challenging lyophilisate !
Drug products produced by lyophilization are typically amorphous and show higher dissolution rate and sulubility. However, undesired crystallization may occur, resulting in a lower dissolution rate or even undesirable particles. Holodiag performs specific investigations to identify crystalline particles, their origin in order to solve these situations.
BioFit Strasbourg 2022
Holodiag will attend as a visitor the new edition of BioFit based in Strasbourg this year ! See you there in three weeks !
CPhI Frankfurt 2022
Are you facing issues or are you looking for scientific discussions related to solid state characterization, polymorphism, crystallization processes ? Holodiag attends CPhI in Frankfurt as a visitor, can’t wait to meet you there !
About InfraRed
InfraRed is a well-known technique for molecular structure identification. It is also used to identify polymorphism in solid samples. Holodiag performs these analyses on high potent product down to 50 ng/m3.
PSD, a crucial parameter !
Particle size and shape are crucial parameters in the pharmaceutical industry because it influences many material properties. Consequences are numerous especially for filtration and drying steps. Holodiag provides advanced analytical services for PSD with a Mastersizer 3000 with both dry and liquid mode. Such a system is fully set and qualified under laminar flow hodd which […]
A multitude of samples can be analyzed by XRPD
Various formulations can be analyzed by XRPD to identify the crystal form of an API. Among classical ones, there are: • spray • suppository • capsule • transdermal patche • suspension • ointment • tablet • powder But also unexpected ones ! As: • flea collar • chew stick • IUD for cow • medicated […]
Holodiag is now registred as a supplier on Scientist.com !
The e-commerce marketplace network connects byuers and sellers of scientific research services.
BOS Basel 2022
Holodiag will be at BOS Basel 2022 as an exhibitor next week ! The event will cover discovery, small molecule CMC and biologics CMC outsourcing. You have interest in: • solid state characterization ? (XRPD, Laser PSD, routine QC analyses, development and validation of analyical methods…) • solid state investigations ? (polymorphs, salts, cocristals screenings) […]
Chemspec Frankfurt 2022
Holodiag will be present at Chemspec Europe – Int. Exhibition for Fine & Speciality Chemicals, as a visitor, on next 31rst of May & 1rst of June in Frankfurt ! Dedicated to solid state and crystallization process development for fine chemical industry, Holodiag’s services include: ✔ Physical characterization & control of solid state ✔ Product recovery ✔ Yield […]
